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      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  55 upvotes 1 year ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community Dutasteride actually has different half lives depending on dose

      in Research/Science  37 upvotes 4 months ago
      Dutasteride's half-life varies with dosage, and lower doses can be effective with fewer side effects compared to finasteride. Some users report different side effects with dutasteride and finasteride, and extreme dosages of dutasteride are unnecessary and potentially harmful.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  135 upvotes 1 year ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Foods with sufficient procyanidin b2?

      in Treatment  6 upvotes 4 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Conversation focuses on foods with sufficient procyanidin b2, such as dark chocolate and apples, and the required dosage.

      community Guys, we finally have an alternative to finasteride

      in Research/Science  263 upvotes 1 month ago
      A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.