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GlossaryBioequivalence

...similarity in drug absorption and effect between two formulations

Bioequivalence refers to the relationship between two drugs that have the same active ingredients and are expected to have the same effect on the body. For two drugs to be considered bioequivalent, they must show similar bioavailability, meaning they release their active ingredients into the bloodstream at the same rate and extent. This concept is crucial for approving generic drugs, ensuring they perform just as effectively as their brand-name counterparts.

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research Bioequivalent Assessment of Finasteride Granules in Chinese Healthy Volunteers

January 2009 in “Chinese Journal of Drug Application and Monitoring”

Finasteride granules and tablets work the same in the body.

research Bioequivalent Assessment of Finasteride Tablets

January 2005 in “Chinese New Drugs Journal”

Locally made finasteride tablets work the same as imported ones.

Formulation of a Film-Coated Dutasteride Tablet Bioequivalent to a Soft Gelatin Capsule (Avodart): Effect of Gamma-Cyclodextrin and Solubilizers

research Formulation of a Film-Coated Dutasteride Tablet Bioequivalent to a Soft Gelatin Capsule (Avodart): Effect of Gamma-Cyclodextrin and Solubilizers

4 citations , May 2019 in “Asian Journal of Pharmaceutical Sciences”

Created tablet similar to Avodart using γ-cyclodextrin and solubilizers.

research Determination of Finasteride in Human Plasma by LC-MS and Study on Its Bioequivalence

January 2007 in “Pharmaceutical Journal of Chinese People's Liberation Army”

The two finasteride tablets are bioequivalent.

Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study

research Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study

1 citations , April 2015 in “Drug research”

New method measures finasteride in plasma, finds two formulations bioequivalent.

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community Out of curiosity, why are Finasteride pills formulated as small tablets, while Dutasteride pills are much larger soft gel capsules?

in Finasteride/Dutasteride 41 upvotes 11 months ago

Finasteride and Dutasteride are used for hair loss, with Dutasteride often in gel form for better bioavailability. Switching from Finasteride to Dutasteride is common, with some users combining treatments like Minoxidil for improved results.

community Switched Finasteride Brands, Hair, Scalp and Skin Declining

in Finasteride/Dutasteride 10 upvotes 9 months ago

Switching finasteride brands from Teva to Proscar led to hair and skin issues, suggesting possible differences in effectiveness or quality. Users recommend returning to the original brand that worked well.

community Reminder: you can get dutasteride for $6.33 / month in the United States

in Finasteride/Dutasteride 67 upvotes 1 year ago

Dutasteride can be obtained for $6.33 per month in the US through Cost Plus Drugs, with prescriptions easily switched from finasteride by contacting a doctor. Users discuss various methods to obtain affordable dutasteride, including using online pharmacies and considering generic options, while cautioning against buying from unreliable sources like eBay.