14 citations
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January 2012 in “Proteins” This study's molecular dynamics simulations suggest that electrostatic interactions mainly stabilize peptide binding to human hair keratin, with the protein's dielectric constant significantly affecting free energy calculations.
20 citations
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September 2023 in “Nutrients” In this study, a very-low-calorie diet led to greater weight loss and improvements in hyperandrogenaemia and metabolic markers in obese women with polycystic ovary syndrome compared to a moderate energy deficit approach over eight weeks.
2 citations
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January 2022 in “Rasayan journal of Chemistry” This study analyzed the affinity, stability, and pharmacokinetics of compounds from Sansevieria trifasciata, reporting that three compounds showed promising molecular docking results against the androgen receptor and satisfactory pharmacokinetic profiles, similar to minoxidil, in an in-silico setting.
January 2024 in “Experimental and clinical endocrinology & diabetes” In this study, a low-glycemic index anti-inflammatory diet led to decreased testosterone levels, increased sex hormone-binding globulin, and improved well-being in overweight and obese women with hyperandrogenism, suggesting that diet and lifestyle changes can positively influence clinical symptoms.
2 citations
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November 2024 in “International Journal of Pharmaceutics X” In this study, desmopressin-loaded elastic liposomes (ODEL1) showed improved permeation and drug deposition across rat skin by altering the skin's cohesive energies and causing reversible changes on its surface.