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GlossaryBcl-2 family

regulates cell death and survival through protein interactions

The Bcl-2 family, also known as the B-cell lymphoma 2 family, is a group of proteins that play a crucial role in regulating cell death (apoptosis). These proteins can either promote survival or trigger cell death, and their balance is essential for maintaining healthy tissue function and preventing diseases like cancer.

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research The Senescence–Stemness Alliance: A Cancer-Hijacked Regeneration Principle

68 citations , September 2018 in “Trends in Cell Biology”

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells

research Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells

15 citations , May 2020 in “BMC complementary medicine and therapies”

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.

Protective Effect of Korean Red Ginseng Against Chemotherapeutic Drug-Induced Premature Catagen Development Assessed With Human Hair Follicle Organ Culture Model

research Protective Effect of Korean Red Ginseng Against Chemotherapeutic Drug-Induced Premature Catagen Development Assessed With Human Hair Follicle Organ Culture Model

19 citations , July 2015 in “Journal of Ginseng Research”

Korean Red Ginseng may protect against hair loss caused by chemotherapy.

research Role of the Wnt Signaling Pathway in Keratoacanthoma

2 citations , November 2019 in “Cancer reports”

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

research Pathobiology of Chemotherapy-Induced Hair Loss

218 citations , January 2013 in “The Lancet Oncology”

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

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community The end of balding: We may have just found the secret to hair regrowth

in Technology 676 upvotes 7 months ago

MCL-1 is important for hair follicle stem cell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.