Search
for

    Did you mean ATP-sensitive potassium channels?
    Glossary ATP-sensitive potassium channels

    regulate potassium ion flow based on cellular energy levels

    ATP-sensitive potassium channels (KATP channels) are specialized proteins found in the cell membrane that help regulate the flow of potassium ions in and out of the cell. These channels are sensitive to the levels of ATP (adenosine triphosphate), the cell's main energy currency, and they open or close in response to changes in ATP concentration. This mechanism allows the channels to play a crucial role in linking the cell's metabolic state to its electrical activity, which is important in various physiological processes such as insulin release, muscle contraction, and neuronal activity.

    Related Terms

    Research 10 of 1000+

    1. Human hair follicles contain two forms of ATP‐ sensitive potassium channels, only one of which is sensitive to minoxidil The FASEB Journal · 2008 · 102 citations
    2. The ATP sensitive potassium channel (KATP) is a novel target for migraine drug development Frontiers in Molecular Neuroscience · 2023 · 13 citations
    3. The Emerging Structural Pharmacology of ATP-Sensitive Potassium Channels Molecular pharmacology · 2022 · 5 citations
    4. 507 Trial to investigate the role of ATP-sensitive potassium channels (KATPc) in dermal papilla cells (DPCs) Journal of Investigative Dermatology · 2024
    5. Investigations into the roles of potassium channels in hair growth : studies confirming the presence of several ATP-sensitive potassium (K+ATP) channels in hair follicles and exploring their mechanism of action using molecular biological, cell culture, organ culture and proteomic approaches Bradford Scholars (University of Bradford) · 2010
    6. Minoxidil prevents 3,4-methylenedioxymethamphetamine-induced serotonin depletions: role of mitochondrial ATP-sensitive potassium channels, Akt and ERK Journal of Neurochemistry · 2008 · 22 citations
    7. Inhibitory effects of the ATP-sensitive potassium channel openers cromakalim, pinacidil and minoxidil on the carbachol–response curve in porcine detrusor muscle Arab Journal of Urology · 2012 · 3 citations
    8. The Role of ATP-Sensitive Inward Rectifier Potassium Channels In The Regulation of Reactive Oxygen Species In The Western Honey Bee, APIS Mellifera L. 2022
    9. Pharmacological evidence for the involvement of adenosine triphosphate sensitive potassium channels in chloroquine-induced itch in mice Pharmacological Reports · 2017 · 9 citations
    10. Immunohistochemical, pharmacovigilance, and omics analyses reveal the involvement of ATP-sensitive K+ channel subunits in cancers: role in drug–disease interactions Frontiers in Pharmacology · 2023 · 3 citations
    All research results →

    Learn

    — no results

    Try a deeper search in learn →

    Community

    — no results

    Try a deeper search in community →