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Glossary Anti-inflammatory Effects

reduce inflammation and alleviate related symptoms in the body

Anti-inflammatory effects refer to the ability of a substance or treatment to reduce inflammation in the body. Inflammation is the body's natural response to injury or infection, but chronic inflammation can lead to various health issues, including autoimmune diseases and conditions like alopecia. Anti-inflammatory effects can help alleviate symptoms, reduce pain, and improve overall health by targeting the underlying inflammatory processes.

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Research

5 / 1000+ results

research Anti-inflammatory effects on murine macrophages of ethanol extracts of Lygodium japonicum spores via inhibition of NF-κB and p38

5 citations , July 2017 in “Molecular Medicine Reports”

This study observed that ethanol extracts of Lygodium japonicum spores significantly reduced inflammatory responses in LPS-stimulated murine macrophages in vitro by negatively regulating p38 MAPK and NF-κB.

research Ketoconazole-p Aminobenzoic Cocrystal Exhibits a Potent Anti-inflammatory Effect on the Skin of BALBc Mice

April 2021 in “Research Square (Research Square)”

This study found that the new cocrystal formulation KET-PABA improved the antimycotic efficiency of ketoconazole and induced an anti-inflammatory response without causing skin sensitization in mice.

Extracellular Vesicles Released by Hair Follicle and Adipose Mesenchymal Stromal Cells Induce Comparable Neuroprotective and Anti-Inflammatory Effects in Primary Neuronal and Microglial Cultures

research Extracellular vesicles released by hair follicle and adipose mesenchymal stromal cells induce comparable neuroprotective and anti-inflammatory effects in primary neuronal and microglial cultures

May 2023 in “Cytotherapy”

This study found that medium/large extracellular vesicles derived from hair follicle and adipose tissue mesenchymal stromal cells both demonstrated significant neuroprotective and anti-inflammatory effects in cell cultures, highlighting their potential use as biopharmaceuticals for treating neurodegenerative diseases.

Anti-Inflammatory Effects in LPS-Treated RAW 264.7 Cells and the Influences on Drug Metabolizing Enzyme Activities by the Traditional Herbal Formulas, Yongdamsagan-Tang and Paljung-San

research Anti-inflammatory Effects in LPS-treated RAW 264.7 Cells and the Influences on Drug Metabolizing Enzyme Activities by the Traditional Herbal Formulas, Yongdamsagan-Tang and Paljung-san

December 2021 in “Daehanhanuihakoeji”

This study suggests that combining finasteride with traditional herbal formulas Yongdamsagan-tang or Paljung-san may not interfere with drug metabolism while potentially enhancing anti-inflammatory effects for treating benign prostatic hyperplasia.

research Antioxidant potential, anti-inflammatory activity, antidiabetic and cardioprotective effect of Microsechium helleri(Peyr.) Cong.

May 2021 in “Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas”

This study found that ethanolic extracts of Microsechium helleri showed notable antioxidant, hypoglycemic, and cardioprotective activities, while chloroformic extracts exhibited significant anti-inflammatory effects in experimental models.

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Community Join

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community Rosemary Oil for inflammatory hairloss? Recommendations?

5 upvotes 1 year ago

A user with seborrheic dermatitis and traction alopecia is seeking alternatives to minoxidil for hair loss, considering rosemary oil for its anti-inflammatory properties. They express concerns about potential side effects and effectiveness of various treatments, including rosemary oil, caffeine, and Redensyl.

community Hair Loss “Cure” for Inflammation: Topical Roflumilast

in Research/Science 32 upvotes 8 months ago

Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

59 upvotes 5 months ago

Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

community Does ketoconazole reduce systemic DHT by much?

in Treatment 6 upvotes 1 year ago

Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is mainly used for its anti-fungal and anti-inflammatory effects. It is not a replacement for finasteride, which is recommended by some users despite concerns about side effects.

community Topical caffeine as an adjunct treatment. I think this should be considered.

4 upvotes 3 years ago

Topical caffeine is suggested as a beneficial adjunct treatment for hair growth due to its anti-fibrotic, anti-inflammatory, antioxidant, and other properties. There is skepticism about its effectiveness, especially at low concentrations like in Alpecin liquid.

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Learn

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learn Low Level Laser Therapy

laser therapy for anti-inflammatory and likely insignificant hair regrowth effects

learn Hydrocortisone

a synthetic cortisol used for anti-inflammatory effects

learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

learn Lavender

plant and natural oil with antimicrobial and some anti-androgenic effects

learn Cetirizine

popular antihistamine showing promise for hair loss as an anti-inflammatory and prostaglandin inhibitor

What makes cetirizine a unique anti-inflammatory option for your scalp? Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is one small unblinded pilot study in pattern hair loss, so scalp use is off-label and experimental.

learn Centella

Sensitive to hormones? A centella scalp mask may help ease hidden inflamm Centella asiatica has anti-inflammatory and wound-healing effects in animal and cell studies, but no published research has tested a centella scalp mask on the human scalp, in hormonal contexts or otherwise, and no community reports were found of one being used this way.

learn procapil

Tried everything and still getting bald patches? Procapil may help calm the immune response Procapil is a cosmetic ingredient complex; laboratory studies of its individual ingredients report anti-inflammatory effects, but no published clinical trial has tested it in alopecia areata or any other immune-related hair loss. Spreading bald patches should be assessed by a dermatologist.

learn Baicapil

Struggling with patchy hair loss like alopecia areata? Baicapil might help by reducing inflammation and reactivating growth. There is no published trial of Baicapil in alopecia areata. The anti-inflammatory and hair-density claims come from the ingredient's manufacturer and from laboratory work on its plant extracts, in people with androgenetic-type hair loss rather than autoimmune patchy hair loss.

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Clinics

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Experts

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16
Dermatologist
Andi Iryanti, M. Biomed
Indonesia

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Andi Iryanti, M. Biomed