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research In Vitro and In Vivo Anti-Aging Effect of Coffee Berry Nanoliposomes

13 citations , September 2023 in “Molecules”

This study found that encapsulating coffee berry extract in nanoliposomes improved its stability, reduced toxicity, and enhanced its anti-aging effects on skin elasticity and lightening more than free extract.

research Effect of Coffee Berry Extract on Anti-Aging for Skin and Hair—In Vitro Approach

8 citations , June 2022 in “Cosmetics”

This study found that coffee berry extract demonstrated anti-aging properties in skin and hair cells, showing significant anti-collagenase activity and stimulating hair-related gene expression, suggesting its potential for use in cosmeceuticals.

research Phytochemical profiling and evaluation of the anti-aging and anti-inflammatory potential of cultivated Eclipta alba (L.)

November 2023 in “South African journal of botany”

This study found that Eclipta alba (L.) cultivated in France exhibited significant anti-inflammatory, antioxidant, and anti-collagenase activities, attributed mainly to compounds like wedelolactone and demethylwedelolactone, suggesting potential use as an anti-aging cosmetic ingredient.

research Anti-Aging, Anti-Inflammatory, and Cytoprotective Properties of Lactobacillus- and Kombucha-Fermented C. pepo L. Peel and Pulp Extracts with Prototype Skin Toner Development

4 citations , October 2025 in “Molecules”

This study concluded that extracts from fermented pumpkin peel and pulp, processed with Lactobacillus strains and kombucha, may serve as multifunctional cosmetic ingredients, offering antioxidant protection, anti-aging, and skin regeneration benefits by demonstrating cytoprotective effects and reducing inflammatory cytokines in cell assays.

research Effects of Polygoni Multiflori Radix on the Elastase, and Collagenase Activities and the Procollagen Synthesis in Hs68 Human Fibroblasts

2 citations , January 2014 in “The Korea Journal of Herbology”

This study found that Polygoni Multiflori Radix (PMR) reduced collagenase and elastase activity after UVB damage in fibroblasts, suggesting potential anti-aging properties for cosmetic use.

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Community Join

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community A less common type of hairloss case

5 upvotes 5 months ago

High-dose Lysine and Histidine supplements caused curly/kinky hair and shedding due to Elastin dysfunction. Minoxidil, white tea, and dark grape juice were mentioned as treatments to inhibit Elastase and mimic Lysyl Oxidase.

community Comprehensive Microneedling Guide

292 upvotes 4 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community Is it worth using anti-hair loss shampoo?

in Product 2 upvotes 7 months ago

Anti-hair loss shampoos, like the one with rosemary, quillaja, and jaborandi extracts, mainly support scalp health but are not effective for hair regrowth compared to treatments like finasteride or minoxidil. Ketoconazole 2% is noted as the only effective anti-hair loss shampoo, while others are often considered scams.

community Anti inflammatories as an adjunct treatment

1 upvotes 8 months ago

Anti-inflammatories like curcumin, quercetin, and vitamin E may help with hair loss when used alongside treatments like finasteride and dutasteride. Ketoconazole is also noted for reducing scalp inflammation and improving scalp health.

community Anti-androgen use causing testicular pain?

in Finasteride/Dutasteride 5 upvotes 1 year ago

Switching from topical finasteride to oral Dutasteride and using Fluridil caused persistent testicular discomfort. The discomfort did not subside after stopping Fluridil, raising concerns about Dutasteride's role.

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Learn

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learn GT20029

What is GT20029 and how does it work as a topical anti-androgen for hair loss? GT20029 is a topical anti-androgen that degrades androgen receptors to combat hair loss.

learn Aminexil

Aminexil: Can I combine it with anti-hair loss shampoos or will it lose effectiveness? You can safely combine Aminexil with anti-hair loss shampoos for enhanced effectiveness.

learn Cetirizine

What makes cetirizine a unique anti-inflammatory option for your scalp? Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is one small unblinded pilot study in pattern hair loss, so scalp use is off-label and experimental.

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Experts

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Dermatologist
Andi Iryanti, M. Biomed
Indonesia

Clinics

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Andi Iryanti, M. Biomed