Topical anti-androgen sold as a cosmetic lotion
Nonsteroidal anti-androgen, originally a prostate cancer drug
a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
Experimental topical anti-androgen, also known as KX-826
- Can pyrilutamide be used by both men and women, or only in specific cases? Pyrilutamide (KX-826) is an investigational topical anti-androgen that has been trialled in men and women but is not approved for hair loss anywhere. Its sponsor reports one failed (2023) and one successful (2026) Phase III in men, none of it peer-reviewed; long-term safety is unknown, and anti-androgens are not considered appropriate in pregnancy.
Experimental topical anti-androgen sold as a research chemical
- HMI-115: Frequently Asked Questions About Hair Loss Treatment HMI-115 is an investigational anti-prolactin-receptor antibody being trialled for androgenetic alopecia. It is not approved anywhere; its hair-loss evidence is a 16-person Phase 1b announced only by press release, plus a completed 192-man Phase 2 in China whose results are not yet published.