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Did you mean Antiandrogen Therapy?

Glossary Antiandrogen Therapy

reduces or blocks male hormones to treat certain conditions

Antiandrogen Therapy, also known as androgen deprivation therapy (ADT), is a treatment that reduces the levels or blocks the effects of androgens (male hormones like testosterone) in the body. This therapy is commonly used to treat conditions like prostate cancer and androgenic alopecia (male pattern baldness) by slowing the growth of cancer cells or reducing hair loss, respectively.

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Research

5 / 1000+ results

Impact of Anti-Androgen Therapies on COVID-19 Susceptibility: A Case-Control Study in Male Population from Two COVID-19 Regional Centers of Lombardy, Italy

research Impact of anti-androgen therapies on COVID-19 susceptibility: a case-control study in male population from two COVID-19 regional centers of Lombardy (Italy)

4 citations , April 2020 in “medRxiv (Cold Spring Harbor Laboratory)”

This case-control study from Lombardy, Italy, observed that men over 55 taking 5-alpha reductase inhibitors for benign prostatic hyperplasia were hospitalized for COVID-19 at a lower rate than age-matched controls, suggesting potential protective effects against severe disease.

research Antiandrogens as Therapies for COVID-19: A Systematic Review

6 citations , January 2024 in “Cancers”

This systematic review found that antiandrogens do not appear to protect against SARS-CoV-2 infection or reduce COVID-19 severity, suggesting their use is not advisable for COVID-19 treatment.

research Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris

7 citations , December 2019 in “American Journal of Clinical Dermatology”

This review discusses the potential efficacy of topical antiandrogen therapies for treating androgenetic alopecia and acne vulgaris, finding promising results but highlighting the need for more comprehensive studies.

research Use of Antiandrogens as Therapeutic Agents in COVID-19 Patients

5 citations , December 2022 in “Viruses”

This review highlights recent insights into using antiandrogens as preventive and therapeutic measures against COVID-19, emphasizing their role in blocking viral infection by modulating androgen-mediated host protease TMPRSS2 and cell entry protein ACE2, with varying success in clinical trials.

research Use of Antiandrogens as Therapeutic Agents in COVID-19 Patients

November 2022

This review summarizes the latest updates on using antiandrogens as potential prophylactic and therapeutic options for COVID-19, highlighting that androgen-mediated regulation of factors like TMPRSS2 and ACE2 is involved in SARS-CoV-2 infection, suggesting a strategy to block viral entry into cells.

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Community Join

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community I Get Side-Effects from Anti-Androgens

8 upvotes 6 years ago

Someone looking for solutions to their hair loss, who has tried and failed to tolerate anti-androgen treatments such as finasteride, CB-03-01, RU58841, and Eucapil. The user is seeking advice and understanding of their extreme sensitivity to these treatments.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

2 upvotes 1 year ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

community When meds don't work how long is too soon before giving up?

7 upvotes 2 weeks ago

A user has been using finasteride, minoxidil, and microneedling for hair loss but continues to experience thinning and has been rejected for a hair transplant due to a thin donor region. They are considering switching to dutasteride and exploring other treatments like mesotherapy, PRP, and topical anti-androgens, while also contemplating shaving their head.

community 8 months of therapies, finasteride, minoxidil and more

in Progress Pictures 397 upvotes 5 months ago

The user experienced significant hair regrowth over 8 months using finasteride, minoxidil, and a custom topical mix including progesterone, cortisone, and alpha 5 estradiol. They reported no side effects and noticed improvement around the third month.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 year ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

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Learn

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learn Pyrilutamide

highly targeted anti-androgen that might have minimal systemic effects

Is pyrilutamide a safer alternative to oral antiandrogens like finasteride? Pyrilutamide may be a safer topical alternative to oral antiandrogens like finasteride.
Can pyrilutamide be used by both men and women, or only in specific cases? Pyrilutamide (KX-826) is an investigational topical anti-androgen that has been trialled in both men and women, but it is not approved for hair loss anywhere; the company reports that its China Phase III trial in men met its primary endpoint, but the data come from sponsor announcements rather than peer-reviewed journals, and long-term safety is unknown.
What is pyrilutamide, and how does it help with androgenic alopecia or hair loss caused by DHT? Pyrilutamide (KX-826) is an investigational topical antiandrogen designed to block DHT at the androgen receptor in the scalp rather than lower DHT in the blood. Its sponsor has announced positive Phase III top-line results in China, but none of the data are peer-reviewed and it is not approved as a medicine anywhere.