1 citations
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January 2021 in “Wiadomości Lekarskie” This experimental study on male rats found that a gel containing carbon dioxide extract of hops effectively promoted wound healing in severe acne by enhancing skin regeneration and exhibiting anti-inflammatory, bactericidal, and antimycotic properties.
March 2025 in “Journal of Pakistan Association of Dermatologists” In this randomized clinical trial, the authors reported that after 12 weeks, 5% dapsone gel was more effective than 1% clindamycin phosphate gel in treating mild to moderate acne vulgaris, showing efficacy in 78.2% of patients compared to 52.7% with clindamycin.
5 citations
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May 2024 in “Molecules” This study found that glycyrrhetinic acid, derived from licorice, may help alleviate acne symptoms by regulating lipid synthesis and inflammatory responses through multiple pathways, as observed in both in vitro and in vivo settings.
June 2026 in “International Journal of Drug Delivery Technology” This study developed a Hyaluronic acid-Carbopol liposomal gel co-loaded with Adapalene and Clindamycin Phosphate, optimized to improve skin penetration and anti-acne efficacy, showing enhanced drug delivery, superior clinical effectiveness, and excellent skin tolerability compared to commercial formulations.
January 2026 in “International Journal of Medical Science” This randomized controlled trial reported that combining 0.1% Adapalene with 2.5% Benzoyl Peroxide significantly improved mild acne outcomes in patients compared to Adapalene alone, with greater efficacy noted particularly among females, younger individuals, and those who are non-obese.
