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Glossary Angiogenic

process of forming new blood vessels from existing ones

Angiogenic refers to the process by which new blood vessels form from pre-existing ones. This is crucial for wound healing and the growth of tissues, including hair follicles. In the context of hair and alopecia, promoting angiogenesis can improve blood supply to the scalp, potentially aiding in hair growth and the treatment of hair loss conditions.

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Research

5 / 1000+ results

research Differential expression of steroid 5α-reductase isozymes and association with disease severity and angiogenic genes predict their biological role in prostate cancer

30 citations , June 2010 in “Endocrine Related Cancer”

In this study, dutasteride more effectively reduced prostate cancer cell viability than finasteride in vitro, but did not significantly alter the angiogenic response.

research Different gene expression profile observed in dermal papilla cells related to androgenic alopecia by DNA macroarray analysis

47 citations , July 2004 in “Journal of Dermatological Science”

In this study, decreased expression of BMP2 and ephrin A3 and increased NT-4 gene expression were observed in dermal papilla cells from androgenic alopecia-affected skin, suggesting potential roles in hair growth regulation.

Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia

research Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia

14 citations , December 2016 in “Sexual Medicine”

This study identified differences in adverse symptoms among patients with post-finasteride syndrome based on short and long androgen receptor gene polymorphisms.

research Glutathione S-transferase gene polymorphism, total antioxidant status, and blood pressure changes in androgenic alopecia

May 2025 in “Anadolu Kliniği Tıp Bilimleri Dergisi”

This study found that in male patients with androgenic alopecia, individuals with certain glutathione S-transferase gene polymorphisms exhibited higher oxidative stress and lower antioxidant capacity, although differences were not statistically significant, and oxidative stress appeared to increase with the progression of alopecia stages.

Androgen Receptor Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males with Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia

research Androgen receptor (AR) gene (CAG)n and (GGN)n length polymorphisms and symptoms in young males with long-lasting adverse effects after finasteride use against androgenic alopecia

March 2017 in “European Urology Supplements”

This study found that variations in (CAG)n and (GGN)n polymorphisms in the androgen receptor gene appear to influence symptom severity in men with post-finasteride syndrome.

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Community Join

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community Needle mesotherapy in the treatment of androgenic alopecia

5 upvotes 3 months ago

Mesotherapy with vitamins is unlikely to effectively treat genetic hair loss and may be a waste of money. Taking 0.25 mg of finasteride daily is likely sufficient to slow hair loss, as it provides similar benefits to higher doses with fewer side effects.

community Female diffuse hair loss on spiro with irregular periods (photos) + genetic hair loss

in Female 16 upvotes 1 year ago

A 34-year-old woman is experiencing diffuse hair loss and irregular periods, possibly due to long-term spironolactone use. She is considering minoxidil and finasteride for treatment and seeking medical advice for androgenic alopecia and hormonal imbalances.

community Targeting multiple AGA mechanisms with commonly available substances

4 upvotes 7 years ago

The conversation discusses using a multimodal approach to treat androgenic alopecia, including substances like gamma-linolenic acid, DHA, sulforaphane, melatonin, cetirizine, astaxanthin, fisetin, apigenin, curcumin, limonene, genistein, and berberine. Users also mention using ketoconazole, minoxidil, and low-level laser therapy (LLLT) as part of their hair loss treatment regimens.

community Do these Supplements actually help?

5 upvotes 2 years ago

The conversation is about hair loss, with a focus on the impact of B12 and iron supplements for deficiencies. It suggests that while supplements can help with deficiencies, genetic factors like androgenic alopecia may require treatments like finasteride.

community How long is minoxidil generally effective for if taken alongside finasteride? Forever?

in Minoxidil 10 upvotes 2 years ago

Minoxidil does not maintain efficacy indefinitely when used alone, but its effectiveness may be prolonged when used with finasteride. Finasteride can maintain some degree of efficacy indefinitely.

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Learn

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learn Lavender

plant and natural oil with antimicrobial and some anti-androgenic effects

learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn Overview

learn Melatonin

hormone commonly taken for sleep aid has some topical benefits for hair

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Finasteride

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.

learn Argan oil

Argan oil: Is it useful for androgenic alopecia, or just for making hair look nice? Argan oil primarily improves hair appearance but lacks proven effectiveness for androgenic alopecia.

learn Microneedling

Does microneedling help with all types of alopecia, or only androgenic alopecia? Microneedling is most effective for androgenic alopecia, with limited evidence for other types.

learn Verteporfin

Is Verteporfin effective for both androgenic alopecia and alopecia areata? Verteporfin is not effective for treating androgenic alopecia or alopecia areata.

learn Vitamin B5

Does Vitamin B5 prevent DHT-related androgenic alopecia? Vitamin B5 does not prevent DHT-related androgenic alopecia.

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Experts

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21
Hair System Specialist
Jane Genesi
Marlton, PA, United States

Clinics

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Jane Genesi