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community Cosmo Pharma Lists Breezula Phase 3 Trial on ClinicalTrials.gov

25 upvotes 3 years ago

A phase 3 trial for Breezula (clascoterone solution) to treat male pattern hair loss has been listed, with 726 participants and a completion date of January 2025. Other treatments mentioned include Aneira Pharma's combination of minoxidil and latanoprost, Triple Hair's combination of minoxidil, latanoprost, and finasteride, and a new microneedling and LLLT device called StimuSIL.

community Has anyone used latanoprost either alone or compounded with minoxidil?

in Product 3 upvotes 1 year ago

The conversation is about using a topical solution of latanoprost and minoxidil for hair loss, with concerns about side effects due to a history of gynecomastia. The user is considering this treatment instead of finasteride and is seeking experiences from others.

community Latanoprost- an effective medication

8 upvotes 7 months ago

Latanoprost is discussed as a potential hair loss treatment, noted for its synergy with minoxidil and 5-AR inhibitors, but concerns include its effectiveness on scalp hair, cost, and potential skin darkening. Some users express interest in trying latanoprost or bimatoprost despite limited real-world evidence.

community Latanoprost Application? Once daily? There’s no information available

3 upvotes 2 years ago

A user is starting treatment for hair loss with topical minoxidil, oral finasteride, and is considering adding topical latanoprost but is unsure about the application frequency and method for latanoprost. They are seeking advice from others with experience using these treatments.

community Min/Fin topical prescription also contains Latanoprost?

in Treatment 3 upvotes 1 year ago

A user discusses a topical prescription for hair regrowth containing Minoxidil, Finasteride, and Latanoprost, noting Latanoprost's side effect of promoting eyelash and eyebrow growth. Others share experiences and information about Latanoprost, highlighting its origins as a glaucoma drug and potential side effects.

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Research

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research Nanostructured lipid carriers loaded with an association of minoxidil and latanoprost for targeted topical therapy of alopecia

9 citations , February 2022 in “European Journal of Pharmaceutics and Biopharmaceutics”

This study suggests that a nanostructured lipid carrier formulation delivering minoxidil and latanoprost may enhance effectiveness and tolerability in treating alopecia by targeting hair follicles.

research Latanoprost and minoxidil: Comparative double-blind, placebo-controlled study for the treatment of hair loss

January 2018 in “Surgical and Cosmetic Dermatology”

This study found that treatments with 5% minoxidil, with or without latanoprost, were effective in controlling hair loss and increasing hair strand count in patients with telogen effluvium or androgenic alopecia.

research Nanostructured Lipid Carriers Loaded with an Association of Minoxidil and Latanoprost for Targeted Topical Therapy of Alopecia

January 2021 in “Social Science Research Network”

This study suggests that a nanostructured lipid carrier formulation of minoxidil and latanoprost may effectively target hair follicles and enhance drug penetration for alopecia treatment.

research Comparison of efficacy, safety and satisfaction of latanoprost versus minoxidil, betamethasone and in combination in patients with alopecia areata: A blinded multiple group randomized controlled trial

8 citations , October 2022 in “Dermatologic Therapy”

In this study, the addition of topical latanoprost to betamethasone treatment improved the therapeutic efficacy for patients with patchy alopecia areata, showing more significant hair regrowth compared to minoxidil alone and enhanced outcomes without adverse effects.

research Efficacy of Topical Latanoprost Versus Topical Minoxidil In the Treatment of Alopecia Areata: Clinical and Dermoscopic Study

July 2024 in “International Journal of Medical Arts”

In this study, both topical minoxidil and latanoprost were found to improve dermoscopic features of alopecia areata, with latanoprost showing superior effectiveness; minor side effects included erythema and itching.

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learn Latanoprost

glaucoma medication with hair follicle stimulant effects

Is latanoprost more effective for hair regrowth than minoxidil? No trial has compared latanoprost and minoxidil head to head. Minoxidil has large randomized trials and FDA approval for hair loss, while latanoprost's scalp evidence is a single 24-week pilot in 16 men, so the published evidence does not support latanoprost being the more effective option.
How does latanoprost work to make eyelashes and possibly scalp hair grow? Studies report that latanoprost, a prostaglandin analog, lengthens the anagen (growth) phase of hair follicles, which is the mechanism given for the eyelash thickening seen in glaucoma patients; on the scalp the evidence is one 16-man pilot study and animal work, so the effect there is unproven.
Can latanoprost be safely applied to the scalp, or is it only for eyelashes? Latanoprost is not approved for use on the scalp and its safety there has not been established: the only human scalp evidence is one 24-week pilot trial in 16 men, and clinicians flag irritation, skin darkening and unknown absorption over a large area as open risks.

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

From hypertension to hair: the unexpected story of minoxidil Minoxidil was developed as an oral blood-pressure drug and approved as Loniten in 1979; unwanted hair growth in patients led to topical Rogaine, approved for men in 1988 and for women in 1991. Trials support topical minoxidil for pattern hair loss, while low-dose oral minoxidil is a prescription drug used off-label and needs medical supervision.

learn Bimatoprost

a synthetic prostamide used to treat eyelashes also shows promise for stimulating hair growth on scalp

How does bimatoprost compare to minoxidil for hair regrowth? Minoxidil is FDA-approved for scalp hair loss and backed by decades of large trials; bimatoprost is approved only for eyelashes, and the published scalp evidence is limited to small short studies, so on the scalp it is off-label and experimental.

learn Nanoxidil

learn Tretinoin

the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

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Hair Loss Treatments
Minoxidil Hair Growth LankaMaharagama · LK

Experts

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