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Glossary Androgenic Stimulation

hormones like testosterone influence hair growth and loss

Androgenic stimulation refers to the process by which androgens, a group of hormones including testosterone, influence the growth and function of various tissues in the body. In the context of hair, these hormones can stimulate hair growth in certain areas, like the face and chest, while potentially leading to hair loss on the scalp, a condition known as androgenic alopecia.

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Research

5 / 1000+ results

research 896 Androgens activate lipogenesis through an AKT-independent mTOR pathway stimulation and a limitation of autophagy in an androgen-sensitive sebocyte cell line

April 2019 in “Journal of Investigative Dermatology”

This study demonstrates that DHT-induced lipid synthesis in sebocytes involves the mTOR pathway, suggesting mTOR inhibitors may help modulate androgen-dependent sebum overproduction.

research The role of pre-operative androgen stimulation in hypospadias surgery.

4 citations , December 2014 in “PubMed”

This review suggests that dihydrotestosterone pretreatment may improve cosmetic outcomes in hypospadias repair, but more randomized trials are needed to determine its effectiveness due to currently limited evidence.

research Role of 5α-reductase inhibitors in androgen-stimulated skin disorders.

3 citations , February 2013 in “PubMed”

This review discusses the pathophysiology of androgen-stimulated skin disorders and key clinical trials of 5α-reductase inhibitors for their treatment, but it does not report new clinical results.

research Corrigendum: Stimulation of hair regrowth in an animal model of androgenic alopecia using 2-deoxy-D-ribose

October 2024 in “Frontiers in Pharmacology”

The correction does not change the conclusion that 2-deoxy-D-ribose helps hair regrowth.

research Efficacy Evaluation of a Novel Home-Used Device Based on a Multiple Stimulation Technology on Hair Growth in Patients with Androgenetic Alopecia

1 citations , August 2018 in “Madridge journal of dermatology & research”

This study observed that the Pilogics Hairegen device increased total hair count by 23.2% and terminal hair count by 21.1% in 289 patients with androgenetic alopecia after approximately 20 weeks of use, with no adverse effects reported.

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Community Join

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community Hair growth stimulated by allogenic adipose-derived stem cells supplemented with ATP in a mouse model of dihydrotestosterone-induced androgenetic alopecia

41 upvotes 1 year ago

Adipose-derived stem cells with ATP improved hair regrowth in male and female mice with androgenetic alopecia. The most effective treatments were low dose stem cells with ATP for males and medium dose stem cells with non-liposomal ATP for females.

community Minoxidil is NOT an Anti-androgen. No.

in Research/Science 43 upvotes 9 months ago

Minoxidil is not an anti-androgen; it is a growth stimulator and does not lower DHT like finasteride or dutasteride. Minoxidil can cause side effects like facial swelling and anxiety due to its vasodilator properties.

community Why are there no studies on Topical Vitamin D3 for AGA?

9 upvotes 2 years ago

Topical Vitamin D3 may stimulate hair growth and has been used for Alopecia Areata. There is a question about the lack of research on its use for Androgenetic Alopecia (AGA).

community SCUBE3 and GT20029 could be the closet thing to a cure: Hair Follicle Regeneration and Protection Against DHT

14 upvotes 3 years ago

SCUBE3 and GT20029 are potential treatments for hair loss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.

community Is there any new drug that looks promising ?

26 upvotes 2 years ago

The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

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Learn

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learn Caffeine

the stimulant you know and love can be used topically to stimulate hair

learn Bicalutamide

a nonsteroidal anti-androgen, most commonly used orally for women

learn Adenosine

nucleoside used for hair regrowth stimulant properties

learn Latanoprost

glaucoma medication with hair follicle stimulant effects

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn Finasteride

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.

learn Spironolactone

Who can safely use spironolactone for hair thinning and androgen-related hair loss? Women with androgen-related hair loss can safely use spironolactone under medical supervision.

learn Argan oil

Argan oil: Is it useful for androgenic alopecia, or just for making hair look nice? Argan oil primarily improves hair appearance but lacks proven effectiveness for androgenic alopecia.

learn Metformin

Does metformin help control DHT levels that trigger androgenic alopecia? Metformin has been shown to lower circulating androgens in women with PCOS, but no published study has measured scalp DHT, 5-alpha reductase activity in the follicle, or hair density in anyone taking it — so its effect on pattern hair loss is untested, and it is not a DHT blocker.

learn Microneedling

Does microneedling help with all types of alopecia, or only androgenic alopecia? Microneedling is most effective for androgenic alopecia, with limited evidence for other types.

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