21 citations
,
October 2011 in “British Journal of Dermatology”
This study found that subcutaneous testosterone therapy improved scalp hair growth in a majority of androgen-deficient women who previously reported hair thinning and did not report hair loss as a side effect.
13 citations
,
August 2018 in “Clinical Chemistry”
This study determined that a total testosterone concentration of ≥5.1 nmol/L identified androgen-producing tumors in women with severe hyperandrogenemia, while a lower threshold of ≥2.2 nmol/L was found for diagnosing pathologic hyperandrogenism in postmenopausal women.
2 citations
,
November 2020 in “Fertility Research and Practice”
This study presents a new survey instrument that was cognitively tested for understanding menstrual cycle characteristics and androgen excess, including hirsutism, alopecia, and acne.
45 citations
,
January 2012 in “The Journal of Steroid Biochemistry and Molecular Biology”
This study found that overexpression of AKR1C3 in prostate cancer cells redirected androgen metabolism towards testosterone production, which facilitated cell proliferation, potentially reducing the effectiveness of finasteride treatment.
Switching from topical finasteride to oral Dutasteride and using Fluridil caused persistent testicular discomfort. The discomfort did not subside after stopping Fluridil, raising concerns about Dutasteride's role.
The conversation is about someone planning to start finasteride or RU58841 for hair loss and wanting to know which hormones to test beforehand. They found a package for testing testosterone, free testosterone, estradiol, and DHT, and are asking if these tests are enough.
A 24-year-old male experienced an increase in estradiol levels and symptoms like gynecomastia and excessive sweating after using Minoxidil for hair loss. His estradiol levels decreased after he stopped using Minoxidil.
Using high doses of testosterone with RU58841 to create an androgen-free environment for hair regrowth is suggested, but concerns about heart health and the effectiveness of this approach are raised. Alternatives like topical estrogen, progesterone, and other treatments like finasteride and dutasteride are discussed.
Bicalutamide blocks androgen receptors, preventing testosterone and DHT from binding, which can help with hair loss but may cause feminization. It is not recommended for those who do not want feminization effects.