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Glossary Androgen Production

process of creating male sex hormones like testosterone

Androgen production, also known as androgen synthesis, refers to the process by which the body produces androgens, a group of hormones that play a key role in male traits and reproductive activity. These hormones, including testosterone, are primarily produced in the testes in men and in smaller amounts in the ovaries and adrenal glands in women. Androgens are crucial for the development of male characteristics such as facial hair and a deeper voice, and they also influence muscle mass and libido.

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Research

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research Targets to treat androgen excess in polycystic ovary syndrome

14 citations , September 2015 in “Expert Opinion on Therapeutic Targets”

This review discusses potential treatments for androgen excess in polycystic ovary syndrome and reports no new findings, emphasizing the importance of individualized antiandrogenic management to minimize side effects.

research Defects in Androgen Biosynthesis Causing 46,XY Disorders of Sexual Development

46 citations , October 2012 in “Seminars in reproductive medicine”

This review describes how recent discoveries in genetic defects and alternative pathways in androgen biosynthesis are reshaping our understanding of male sexual differentiation, but it presents no new clinical findings.

research Androgens and androgen receptor action in skin and hair follicles

100 citations , September 2017 in “Molecular and Cellular Endocrinology”

This review discusses the molecular mechanisms of androgens and androgen receptors in skin disorders, particularly androgenetic alopecia, and reports no new clinical results; it highlights potential areas for future treatment development.

research Pathways to inflammation: acne pathophysiology

68 citations , May 2011 in “European Journal of Dermatology”

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

research Effects of finasteride on steroid production and gene expression in male fathead minnow (Pimephales promelas) and medaka (Oryzias latipes)

January 2026

In these aquatic laboratory studies, researchers found that Finasteride reduced dihydrotestosterone levels in fathead minnows and increased gene expression related to androgen pathways in both minnows and medaka, indicating potential conservation of pharmaceutical effects on androgen biosynthesis across different species.

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Community Join

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community Minoxidil is a 5ar inhibitor according to research

150 upvotes 11 months ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

community Why Fin/Dut Isn't Working for You GPR133: a new hairloss mechanism + Steroid Hair Loss Deep Dive

6 upvotes 1 month ago

Hair loss may be linked to the GPR133 receptor, independent of the androgen receptor pathway. Treatments like finasteride, dutasteride, minoxidil, RU58841, and KX-826 show varying results, with hair loss persisting due to high testosterone and GPR133's role.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 44 upvotes 2 years ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community SCUBE3 and GT20029 could be the closet thing to a cure: Hair Follicle Regeneration and Protection Against DHT

14 upvotes 3 years ago

SCUBE3 and GT20029 are potential treatments for hair loss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.

community I had claude create a protocol only using fda approved drugs.

4 upvotes 8 months ago

A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

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Learn

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learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Epidermal Growth Factor

learn Stem Cell Factor

learn Overview

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Clinics

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Hair Systems
PM Production PerruquesLiège · BE

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