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Step-Down Approach to Concentration of Intralesional Triamcinolone Acetonide in Treatment of Scalp Patchy Alopecia Areata: Insights from an Open-Label Randomized Trial

research Step-down approach to concentration of intra-lesional triamcinolone acetonide in treatment of scalp patchy alopecia areata: insights from an open-label randomized trial

November 2025 in “Archives of Dermatological Research”

Using a higher concentration of triamcinolone acetonide leads to faster hair regrowth in scalp patchy alopecia areata.

Trichoscopic Clues for Diagnosis of Patchy Scalp Alopecia in Egyptian Patients

research Trichoscopic Clues for Diagnosis of Patchy Scalp Alopecia in the Egyptian Patients

January 2019 in “The Egyptian Journal of Hospital Medicine”

In this study, researchers evaluated trichoscopic features in 500 Egyptian patients with patchy hair loss and found specific patterns, such as perifollicular scale with 90% sensitivity and 99.5% specificity, which effectively aid in diagnosing primary cicatricial alopecias.

research A Retrospective Comparative Study of Two Concentrations of Intralesional Triamcinolone Acetonide in the Treatment of Patchy Alopecia Areata on the Scalp

6 citations , November 2020 in “Clinical Cosmetic and Investigational Dermatology”

This study found that intralesional injections of triamcinolone acetonide at 5 mg/mL are as effective and safe as 10 mg/mL for treating patchy alopecia areata on the scalp, with similar hair regrowth rates, side effects, and recurrence observed between the two dosages.

research A case of neurodermatitis circumscipta of scalp presenting as patchy alopecia

11 citations , January 2013 in “International Journal of Trichology”

This article reports a case of neurodermatitis where a combination of intralesional steroids, oral doxepin, and psychotherapy resulted in complete symptom remission and hair regrowth, highlighting the importance of addressing emotional factors in treatment.

research Lupus Panniculitis of the Scalp Presenting as a Patchy Nonscarring Alopecia: Report of an Uncommon Case

September 2025 in “American Journal of Dermatopathology”

In this report, a unique case of lupus panniculitis of the scalp was diagnosed in a 40-year-old woman presenting with non-scarring patchy alopecia, which responded completely to oral prednisolone and methotrexate treatment.

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Learn

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learn Scalp Micropigmentation

What is Scalp Micropigmentation and how does it help people with visible hair loss? Scalp Micropigmentation creates the illusion of hair follicles on the scalp for visible hair loss.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Bimatoprost

What do the latest studies say about bimatoprost for scalp hair growth? Bimatoprost is approved only for eyelashes; a 30-person pilot found it beat a topical steroid on patches of alopecia areata, but the two registered Allergan trials in male pattern hair loss were never published and never taken further, so scalp use stays off-label and experimental.

learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

learn HMI-115

much-hyped research compound targeting prolactin receptor in scalp

learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Omega 3

Does omega-3 help with scalp inflammation or irritation linked to conditions like dandruff or alopecia? Omega-3 may help reduce scalp inflammation linked to dandruff and alopecia.

learn Hydrocortisone

When should hydrocortisone be used for hair loss — is it only for irritated scalps or also alopecia areata? Hydrocortisone is a low-potency topical steroid whose labelled use is calming scalp irritation such as dermatitis; for alopecia areata no verified human trial supports it on its own, and dermatologists generally use stronger prescription corticosteroids instead.

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Community Join

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community Minoxidil is a 5ar inhibitor according to research

150 upvotes 11 months ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

413 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community My understanding of how androgenetic alopecia works (plus FIN and DUT)

18 upvotes 4 years ago

Androgenetic alopecia is affected by scalp DHT levels, not sensitivity, with treatments like finasteride and dutasteride aiming to optimize these levels. Personalized DHT management is crucial for effective hair growth.

community 29M alopecia or normal hair fall but something worked. Just wanted to share.

4 upvotes 1 year ago

A 29-year-old male experienced hair loss and found improvement using a combination of onion hair oil, castor oil, ketoconazole shampoo, and aloe vera gel with vitamin E, while discontinuing minoxidil and finasteride due to side effects. He emphasizes the importance of scalp massage and oiling for hair growth and reduced hair fall.

community The mechanism of androgenic alopecia

36 upvotes 11 months ago

DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

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Clinics

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46
SMPHair Loss Treatments
The Alopecia Doctor Hair and Scalp SpaHouston, TX · US

Experts

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24
Trichologist
Kirsten J. Scalp
Greenville, SC, United States

Kirsten J. Scalp