January 2025 in “Dermatologic Therapy” This review article reports that oxidative stress is a key mechanism in the development of androgenetic alopecia, interacting with genetic and hormonal factors to damage hair follicle cells and potentially informing future treatment strategies.
52 citations
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April 2004 in “Journal of The American Academy of Dermatology” This article proposes three mechanisms by which dihydrotestosterone may contribute to baldness but reports no new research findings.
January 2024 in “Journal of Biosciences and Medicines” This research suggests that recent discoveries of signaling pathways in androgenic alopecia may pave the way for targeted therapies, providing potential new treatment options beyond the current FDA-approved drugs, minoxidil and finasteride.
October 2022 in “Hair Transplantation” This review discusses genetic factors and associated diseases linked to androgenetic alopecia but reports no new clinical findings.
30 citations
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December 2017 in “Medical Hypotheses” This review evaluates dihydrotestosterone's role in androgenic alopecia and proposes a model suggesting that chronic scalp tension and inflammation contribute to hair follicle miniaturization, identifying fibrosis, calcification, and tension as treatment targets.
