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research PIK3CA Gain-Of-Function Mutation In Schwann Cells Leads To Severe Neuropathy And Aerobic Glycolysis Through A Non-Cell Autonomous Effect

June 2025 in “Proceedings of the National Academy of Sciences”

A PIK3CA mutation in Schwann cells causes severe nerve damage and increased glycolysis, but early treatment can help.

research HIF1A Stabilization in the ORS of Human Hair Follicles Promotes Aerobic Glycolysis and Synthesis of Angiogenic Factors

April 2019 in “Journal of Investigative Dermatology”

Stabilizing HIF1A in hair follicles may boost hair growth by enhancing energy production and blood vessel formation.

research A Multidisciplinary Lifestyle Intervention for Women with Polycystic Ovary Syndrome: The Role of a Pulse-Based Diet and Aerobic Exercise on Reproductive, Cardio-Metabolic, and Quality of Life Outcomes

May 2018 in “University Library - University of Saskatchewan (University of Saskatchewan)”

A pulse-based diet with exercise improved PCOS health more than another diet, but benefits didn't last long-term.

research Metabolism of Freshly Isolated Human Hair Follicles Capable of Hair Elongation: A Glutaminolytic, Aerobic Glycolytic Tissue

71 citations , June 1993 in “Journal of Investigative Dermatology”

research A Systematic Review of the Effects of Exercise on Hormones in Women with Polycystic Ovary Syndrome

98 citations , May 2020 in “Journal of Functional Morphology and Kinesiology”

Exercise, especially vigorous aerobic and resistance training, can improve hormone levels in women with PCOS.

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community Cardio for more than 60 minutes reduces DHT levels and improve hair growth

in Research/Science 126 upvotes 9 months ago

Long aerobic exercise (over 60 minutes) can reduce DHT levels and improve hair health. Some users discuss using Tadalafil (Cialis) to further reduce DHT after exercise, while others mention using treatments like Minoxidil, Finasteride, and RU58841 for hair growth.

community New molecule PP405 vs exercise

in Research/Science 40 upvotes 7 months ago

PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

community What's an anecdotal treatment you nevertheless swear by?

in Product 10 upvotes 11 months ago

Stemoxydine is highly recommended for hair loss, preferred over Minoxidil due to fewer side effects and dependency. The user also uses finasteride, Pur'ador shampoo, and suggests cold showers and spicy food as part of their routine.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

in Research/Science 2 upvotes 11 months ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 413 upvotes 11 months ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

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