June 2025 in “Proceedings of the National Academy of Sciences” In this study, a mouse model with a PIK3CA gain-of-function mutation in Schwann cells revealed unique communication with neighboring cells and a glycolytic shift in peripheral nerves, and early alpelisib treatment significantly improved symptoms, though efficacy declined with delayed administration due to limited drug penetration.
April 2019 in “Journal of Investigative Dermatology” Stabilizing HIF1A in hair follicles may boost hair growth by enhancing energy production and blood vessel formation.
May 2018 in “University Library - University of Saskatchewan (University of Saskatchewan)” This study found that in women with polycystic ovary syndrome, a pulse-based diet was more effective than the TLC diet at improving insulin sensitivity and cardiometabolic risk factors, although both diets improved PCOS-specific health outcomes.
71 citations
,
June 1993 in “Journal of Investigative Dermatology” 133 citations
,
July 1994 in “Journal of Dermatological Science” In this study, the researchers developed an in vitro model that maintains human hair follicles to grow at in vivo rates and observed that factors like EGF and IGF-I influence hair follicle growth and catagen entry.