15 citations
,
July 2017 in “PubMed” This study observed that injecting a combination of human cultured dermal papilla and epithelial cells induced hair growth in a mouse model.
96 citations
,
April 2007 in “Journal of Investigative Dermatology” In this study, co-grafting human keratinocytes with murine dermal papilla-enriched cells produced hair follicle-like structures, but without regular hair formation, suggesting anomalous folliculogenesis.
15 citations
,
September 1999 in “British Journal of Dermatology” This study found that epimorphin is closely linked to developing hair follicles in human fetuses, suggesting it plays a significant role in hair follicle morphogenesis.
8 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” This study reported that exogenous R-spondin-1 can restore hair follicle neogenesis in adult mouse cells, highlighting differences in gene expression and signaling pathways between fetal and adult dermal papilla cells.
90 citations
,
August 2004 in “Physiological Genomics” This study found that coculturing human hair follicle keratinocyte stem cells with dermal papilla cells increased expression of the hair-specific keratin 6hf gene, which requires β-catenin/lef-1 signaling for hair differentiation.
