29 citations
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August 2008 in “Current Opinion in Pediatrics”
This review discusses the most common types of alopecia in adolescents and emphasizes the importance of psychosocial support, but reports no new clinical findings.
This study emphasized that trichoscopy and ultraviolet-enhanced follicular dermoscopy enhance diagnostic accuracy in adolescent alopecia, while systemic JAK inhibitors offer promising treatment options, reflecting the need for specialized, etiology-driven approaches and highlighting knowledge gaps in prevention and long-term outcomes.
2 citations
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July 2018 in “Journal of pediatric epilepsy”
This case report describes a 13-year-old girl with epilepsy who experienced hairloss within two months of starting levetiracetam, marking it as the first report of this side effect in this age group.
4 citations
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January 2017 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH”
In this study, alopecia areata was identified as the most common cause of hairloss in children, with histopathological findings similar to those in adults.
Hairloss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.
A permanent hairloss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.
DHT sensitivity at the scalp increases with age, contributing to androgenic alopecia. Treatments like Minoxidil, finasteride, and RU58841 are discussed for managing hairloss.
The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hairloss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hairloss treatments, but the main focus is on the science behind fatty acids and their role in hair health.
Hairloss treatments like Minoxidil, finasteride, and RU58841, focusing on their effectiveness and side effects. It also highlights the disparity in medical research funding between hairloss and conditions like endometriosis.
How do I know if I am a good candidate?Clinics say candidacy depends on stable hair loss, enough donor hair and realistic goals. Younger people with progressing loss need a long-term plan, often including medical treatment, discussed with a doctor.
Are Procyanidin based hair tonics or shampoos effective against androgenic alopecia?Three small trials of topical procyanidin in 29 to 43 men, all run by the company that developed it, reported modest hair-count gains after four to six months. No independent trial has confirmed them, and procyanidin is not an approved treatment for pattern hair loss.
HMI-115: Frequently Asked Questions About HairLoss TreatmentHMI-115 is an investigational anti-prolactin-receptor antibody being trialled for androgenetic alopecia. It is not approved anywhere; its hair-loss evidence is a 16-person Phase 1b announced only by press release, plus a completed 192-man Phase 2 in China whose results are not yet published.
Does caffeine stimulate hair growth or only slow hairloss?Caffeine stimulates hair follicles in laboratory cultures, and one open-label, manufacturer-funded trial in 210 men found a 0.2% caffeine topical non-inferior to minoxidil 5% on an anagen-ratio endpoint. A 2025 systematic review found only a few small controlled trials, mostly rated low or very low quality, and none in alopecia areata.