2 citations
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November 2025 in “Cells” This review presents evidence supporting the potential of adipose-derived stem cell secretome as a promising cell-free therapy for skin repair, emphasizing its application in wound healing, alopecia, skin rejuvenation, and inflammatory skin diseases.
This study found that treatments with adipose-derived stem cell secretome and minoxidil significantly improved hair growth in androgenetic alopecia, with the combination therapy showing the greatest improvement over 12 weeks.
March 2023 in “Clinical Cosmetic and Investigational Dermatology” This commentary reviews methods for delivering adipose-derived mesenchymal stem cell secretome for facial skin rejuvenation and does not report new clinical results; the authors discuss addressing concerns about administration methods and product characterization.
March 2025 in “Archives of Dermatological Research” This study observed that all treatment groups for androgenetic alopecia, using either minoxidil, adipose-derived stem cell secretome, or a combination, showed significant hair growth improvement, with the best results seen in the combination group by week 12, and minimal side effects noted mainly with minoxidil.
October 2021 in “Plastic and reconstructive surgery. Global open” This study found that levels of certain signaling proteins were significantly higher in the alopecia zone compared to other areas, suggesting a role in androgenetic alopecia etiology.