A Comparative Study on Adipose-Derived Mesenchymal Stem Cells Secretome Delivery Using Microneedling and Fractional CO2 Laser for Facial Skin Rejuvenation
March 2023
in “
Clinical Cosmetic and Investigational Dermatology
”
New to Microneedling? There is a guide in the encyclopedia. Read the guide → Studysummary This commentary reviews methods for delivering adipose-derived mesenchymal stem cell secretome for facial skin rejuvenation and does not report new clinical results; the authors discuss addressing concerns about administration methods and product characterization.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The authors of the study on adipose-derived mesenchymal stem cells (ADMSCs) secretome delivery for facial skin rejuvenation respond to feedback by clarifying that their research focuses on comparing microneedling and fractional CO2 laser as delivery methods, rather than exploring the efficacy of the secretome itself. They acknowledge the importance of secretome dosage and characterization but note that specific protein concentrations cannot be disclosed due to proprietary reasons. The study highlights the potential of stem cell secretomes in dermatology, including anti-aging and wound repair benefits, while emphasizing the need for further research on delivery methods.