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Glossary Adhesion Molecules

proteins on cell surfaces that enable cell-to-cell binding

Adhesion molecules are proteins located on the surface of cells that help them stick to each other and to their surroundings. They play a crucial role in various biological processes, such as immune response, wound healing, and the maintenance of tissue structure. For example, in the context of hair biology, adhesion molecules can influence how hair follicle cells interact and function, potentially impacting conditions like alopecia.

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research Adhesion Molecules in Skin Development: Morphogenesis of Feather and Hair^a

45 citations , December 1991 in “Annals of the New York Academy of Sciences”

This study reports that different adhesion molecules play distinct roles in the morphogenesis of feathers and hair, influencing processes such as mesenchymal condensation, epithelial folding, and cell death.

research Immunoexpression of Adhesion Molecules During Human Fetal Hair Development

1 citations , November 2021 in “Revista Científica Hospital Santa Izabel”

This study found that adhesion molecules, specifically integrins and cadherins, are crucial for the down growth and proliferation of hair follicles in human embryos and fetuses.

research Intercellular Adhesion Molecule-1 and Hair Follicle Regression

29 citations , April 2000 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry”

This study found that ICAM-1 expression in murine skin is developmentally regulated and crucial for skin and hair follicle remodeling beyond its recognized role in immune responses.

research Mesenchymal Stem Cells With Modification of Junctional Adhesion Molecule A Induce Hair Formation

8 citations , February 2014 in “Stem cells translational medicine”

This study found that human mesenchymal stem cells overexpressing JAM-A improved hair follicle structure and hair formation in mice by reducing abnormalities such as curved and zigzagged follicles.

research Cell adhesion molecules in inflammatory and neoplastic skin diseases

7 citations , May 1993 in “Journal of the European Academy of Dermatology and Venereology”

This review examines the role of cell adhesion molecules in the pathogenesis of various inflammatory and neoplastic skin diseases, suggesting their potential utility in diagnosis and treatment without presenting new clinical results.

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community Why Fin/Dut Isn't Working for You GPR133: a new hairloss mechanism + Steroid Hair Loss Deep Dive

6 upvotes 2 months ago

Hair loss may be linked to the GPR133 receptor, independent of the androgen receptor pathway. Treatments like finasteride, dutasteride, minoxidil, RU58841, and KX-826 show varying results, with hair loss persisting due to high testosterone and GPR133's role.

community The Real Cause Of Androgenetic Alopecia

675 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

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