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5 / 5 resultslearn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
learn Saw Palmetto
a natural and far less effective alternative to Finasteride
learn Azelaic Acid
acid used for antimicrobial, anti-inflammatory and anti-androgenic properties
learn Rosemary
herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties
Research
5 / 1000+ results![5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction](/images/research/7fe680ad-8571-46ae-ab7c-f81015026bd3/small/13478.jpg)
research 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction
Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.
![5alpha-reductase inhibitors - a new hope in dermatology?](/images/research/bfed771c-e0c5-4df5-9e8f-17fe07ea1b59/small/34427.jpg)
research 5alpha-reductase inhibitors - a new hope in dermatology?
Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.
research 5alpha-reductase inhibitors/finasteride.
![The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals](/images/research/2595df72-e7fa-4bc2-a414-0eb5119d787c/small/20458.jpg)
research The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals
The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.
![Effects of the anti-androgen finasteride on 5alpha-reductase activity in human gingival fibroblasts in response to minocycline](/images/research/f5c8f308-ae9b-4777-9077-b15ffdcd4c9c/small/2176.jpg)
research Effects of the anti-androgen finasteride on 5alpha-reductase activity in human gingival fibroblasts in response to minocycline
Finasteride helps treat hair loss by blocking enzyme activity.
Community Join
5 / 195 resultscommunity Do these two supplements inhibit 5alpha-reductase?
Pumpkin Seed Oil and Perilla Oil (with alpha-lipoic acid, linoleic acid, and oleic acid) are discussed as potential 5alpha-reductase inhibitors. The conversation focuses on their effectiveness for hair loss treatment.
community FCE 28260: A Forgotten 5α-Reductase Inhibition
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community Update: A New Therapeutic Channel - Hair Follicle Glucose Metabolism
Hair loss can be treated by correcting glucose metabolism in hair follicles and using equol as a safer DHT blocker. Production of these treatments is starting soon, and a Discord channel is available for more information.
community Stop Using Salicylic acid on your face if using minoxidil for beard growth
Salicylic acid can reduce the effectiveness of minoxidil for beard growth. Users discuss avoiding salicylic acid when using minoxidil.
community Are topicals with caffeine useful to promote hairgrowth?
The user is asking if caffeine topicals are effective for hair growth, noting they already use Minoxidil and finasteride. They are unsure if caffeine topicals are beneficial or a waste of money.