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    Did you mean 5-alpha-reductase inhibitor?
    Glossary 5-alpha-reductase inhibitor

    blocks enzyme converting testosterone to dihydrotestosterone (DHT)

    A 5-alpha-reductase inhibitor is a type of medication that blocks the enzyme 5-alpha-reductase, which is responsible for converting testosterone into dihydrotestosterone (DHT). By reducing DHT levels, these inhibitors can help treat conditions like male pattern baldness and benign prostatic hyperplasia (BPH).

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    Research 10 of 1000+

    1. Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition Psychoneuroendocrinology · 2018 · 37 citations
    2. Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque. The Journal of Clinical Endocrinology and Metabolism · 1992 · 34 citations
    3. Clinical and hormonal effects of the 5 alpha-reductase inhibitor finasteride in idiopathic hirsutism. The Journal of Clinical Endocrinology and Metabolism · 1994 · 33 citations
    4. Incomplete Recovery of Erectile Function in Rat after Discontinuation of Dual 5‐Alpha Reductase Inhibitor Therapy The Journal of Sexual Medicine · 2012 · 29 citations
    5. Safety and Tolerability of the Dual 5-Alpha Reductase Inhibitor Dutasteride in the Treatment of Androgenetic Alopecia Annals of Dermatology · 2016 · 19 citations
    6. Persistent Erectile Dysfunction after Discontinuation of 5-Alpha Reductase Inhibitor Therapy in Rats Depending on the Duration of Treatment The World Journal of Men s Health · 2018 · 17 citations
    7. Pharmacodynamic modeling of finasteride, a 5 alpha-reductase inhibitor. PubMed · 1995 · 7 citations
    8. Androgenic Efficacy and Mechanism of Glycosides-Based Standardized Fenugreek Seeds Extract Through Aromatase And 5-Alpha Reductase Inhibition Pharmacognosy Journal · 2024 · 1 citations
    9. 5 alpha-reductase inhibition by a new synthetic steroid (PM-9) in cultures of Penicillium crustosum. PubMed · 2002 · 1 citations
    10. SAT-279 The Effect of Chronic 5-alpha Reductase Inhibition on Clinically Apparent and Silent Cardiovascular Events Journal of the Endocrine Society · 2025
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    Community 10 of 1000+

    1. Allopregnanolone deficiency by 5-ari inhibition (fin/dut users) Reddit · 11 Dec 2023
    2. BREAKTHROUGH: I’m a radiochemist and discovered a radioactive isotope scalp serum that OUTPERFORMS Minoxidil and 5-AR inhibitors! (Lab Data Inside) Reddit · 10 Jun 2025
    3. Why does this industry still revolve around 5-AR inhibitors? Reddit · 14 Jun 2021
    4. Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate. Reddit · 11 May 2023
    5. Which Saw Palmetto is good for blocking 5 alpha reductase, Serenoa repens or Chamaerops humilis? Reddit · 26 Jun 2020
    6. 4 months on oral dutasteride + one month and 3 weeks on topical minoxidil 5% Reddit · 23 May 2026
    7. Three months 0.5mg Dutasteride and 5% topical Minoxidil daily Reddit · 22 May 2026
    8. [Discussion] Trichoscopy in sudden-onset AGA: Pathology and reversibility of "Yellow Dots" without 5AR-inhibitors? Reddit · 22 Mar 2026
    9. Guys if you can’t take 5AR inhibitors still get on treatment ASAP Reddit · 6 Jan 2026
    10. Minoxidil is a 5ar inhibitor according to research Reddit · 4 Oct 2025
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    Learn 6 of 24

    1. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    2. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    3. Saw Palmetto Palm-berry extract taken as a supplement
    4. Rosemary Herb whose oil is used in hair care
    5. Neem Oil Oil from the neem tree, used in traditional remedies
    6. Azelaic Acid Acid used in acne and rosacea creams
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