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      research Androgenetic Alopecia: Therapy Update

      May 2023 in “Drugs”
      This comprehensive review analyzes androgenetic alopecia treatments, discussing the mechanisms, costs, efficacy, and safety of FDA-approved drugs like minoxidil and finasteride, as well as newer non-FDA-approved options that have shown effectiveness across various studies.

      research New drugs under investigation for the treatment of alopecias

      26 citations , January 2019 in “Expert Opinion on Investigational Drugs”
      This review explored the new and emerging treatments for androgenetic alopecia and alopecia areata, finding that JAK inhibitors show promise for alopecia areata, while advancements in stem-cell research may eventually lead to new and improved treatments for androgenetic alopecia.

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      learn Clascoterone

      An androgen-receptor blocker approved only for acne (Winlevi 1% cream). A scalp solution is still investigational for hair loss; its sponsor reports positive Phase III results in men, not yet peer-reviewed.
      • Is clascoterone suitable for both men and women? Clascoterone is not approved for hair loss in either sex — the approved product is a 1% acne cream. The scalp version has completed phase III trials in men with sponsor-reported positive results; in women the only data is a company-reported phase II significant in one subgroup, so use is off-label and investigational for both.