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    Glossary5α-reductase enzyme

    converts testosterone into the more potent dihydrotestosterone (DHT)

    The 5α-reductase enzyme is responsible for converting testosterone into dihydrotestosterone (DHT), a more potent androgen hormone. This enzyme plays a significant role in the development of male characteristics and is also implicated in conditions like androgenic alopecia (male pattern baldness) and benign prostatic hyperplasia (BPH).

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    Products matching "5 alpha-reductase enzyme"

    Tracking 2 products like 96 MinoDuta and 273 Finasterid Kaufen from by companies like MinoxidilMax and Deutschemedz. View all 2 products »

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      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Saw Palmetto

      a natural and far less effective alternative to Finasteride

      learn Azelaic Acid

      acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

      learn Rosemary

      herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties

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      community ghk-cu is potent 5-ar inhibitor?

      in Product  10 upvotes 9 months ago
      GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 2 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Dermatologist didn’t want to write for Dutasteride and oral minox, instead gave me script for this 12.5% minox with tretinoin,azelaic acid, and topical finasteride. It’s 55$ a month, is it worth it?

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      The conversation discusses a prescribed hair loss treatment combining 12.5% minoxidil with tretinoin, azelaic acid, and topical finasteride, costing $55 a month. One user criticizes the packaging for degrading tretinoin, another suggests it's an overpriced option and recommends topical dutasteride as an alternative due to its higher molecular weight and lower systemic absorption.