Formation of Regulator/Target Gene Relationships During Evolution

    October 2000 in “ Gene ”
    Thomas Schlake, Michael Schorpp, Thomas Boehm
    Studysummary This study found that Foxn1-like genes in fish and mice are functionally equivalent in activating hair keratin genes, whereas changes in the cephalochordate Foxn1-like gene result in inactivity.
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    Research cited in this study 3

    1. Forkhead/Winged-Helix Transcription Factor Whn Regulates Hair Keratin Gene Expression: Molecular Analysis of the Nude Skin Phenotype Developmental Dynamics · 2000
    2. Whn and mHa3 Are Components of the Genetic Hierarchy Controlling Hair Follicle Differentiation Mechanisms of Development · 1999
    3. The Secret Life of the Hair Follicle Trends in genetics · 1992