High-Confidence Cancer Patient Stratification Through Multiomics Investigation of DNA Repair Disorders

    November 2022 in “ Cell Death and Disease ”
    Garik V. Mkrtchyan, Alexander Veviorskiy, Evgeny Izumchenko … Morten Scheibye‐Knudsen
    Studysummary In this study, the researchers identified CEP135 as a biomarker linked to poor sarcoma survival and suggested PLK1 as a potential therapeutic target for sarcoma patients with high CEP135 expression.
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    3. Multicentric Parallel Phase II Trial of the Polo-Like Kinase 1 Inhibitor BI 2536 in Patients With Advanced Head and Neck Cancer, Breast Cancer, Ovarian Cancer, Soft Tissue Sarcoma, and Melanoma. The First Protocol of the European Organization for Research and Treatment of Cancer Network of Core Institutes European Journal of Cancer · 2010