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    Col4a2-eGFP Mouse Model Reveals the Molecular and Functional Dynamics of Basement Membrane Remodelling in Hair Follicle Morphogenesis

    November 2023 in “ bioRxiv (Cold Spring Harbor Laboratory) ”
    Duligengaowa Wuergezhen, Eleonore Gindroz, Ritsuko Morita … Hironobu Fujiwara

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study used a novel fluorescent tagging method in mice to observe collagen IV dynamics during hair follicle development, revealing that alterations in basement membrane turnover can influence epithelial progenitor cell behavior and organ morphology by affecting cell proliferation and movement.
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    Research cited in this study 4

    1. Mapping the Molecular and Structural Specialization of the Skin Basement Membrane for Inter-Tissue Interactions Nature communications · 2021
    2. Multi-Tasking Epidermal Stem Cells: Beyond Epidermal Maintenance Development, Growth & Differentiation · 2018
    3. Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration Nature · 2012
    4. The Basement Membrane Of Hair Follicle Stem Cells Is A Muscle Cell Niche Cell · 2011