Efficacy of JAK 1/2 Inhibition in the Treatment of Diffuse Non-Scarring Alopecia Due to Systemic Lupus Erythematosus

    January 2020 in “ Annals of the rheumatic diseases ”
    Keisuke Maeshima, Hirotaka Shibata
    Studysummary In this study, baricitinib improved the resolution of arthritis or rash in patients with systemic lupus erythematosus, but outcomes for skin involvement like alopecia were not reported.
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    Research cited in this study 5

    1. The Role of Janus Kinase Inhibitors in the Treatment of Alopecia Areata: A Systematic Review Dermatologic therapy · 2019
    2. The Influence of Interferon on Healthy and Diseased Skin Cytokine · 2018
    3. Hair and Scalp Changes in Cutaneous and Systemic Lupus Erythematosus American Journal of Clinical Dermatology · 2018
    4. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    5. Severe Diffuse Non-Scarring Hair Loss in Systemic Lupus Erythematosus: Clinical and Histopathological Analysis of Four Cases Journal of the European Academy of Dermatology and Venereology · 2011