A Multi-Technique Approach to the Study of Structural Stability and Desolvation of Two Unusual Channel Hydrate Solvates of Finasteride

    September 2011 in “ Journal of Pharmaceutical Sciences ”
    Stephen Byard, Anuji Abraham, Paul J. T. Boulton … Paul Hodgkinson
    Studysummary This study found that the desolvation of finasteride hydrate solvates is highly dependent on the physical environment, complicating investigations but providing insight through complementary analysis techniques.
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    Research cited in this study 4

    1. Three Isostructural Solvates of Finasteride and Their Solid-State Characterization European Journal of Pharmaceutical Sciences · 2009
    2. Use of Rotary Echoes in ²H Magic-Angle Spinning NMR for the Quantitative Study of Molecular Dynamics Chemical Physics Letters · 2009
    3. Structural Study of Polymorphs and Solvates of Finasteride Journal of Pharmaceutical Sciences · 2007
    4. Structural Characterization of Polymorphs and Molecular Complexes of Finasteride Journal of Molecular Structure · 1999

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    1. A Multi-Technique Approach to the Study of Structural Stability and Desolvation of Two Unusual Channel Hydrate Solvates of Finasteride Journal of Pharmaceutical Sciences · 2011