Treatment of hirsutism by finasteride and flutamide in women with polycystic ovary syndrome

    August 1997 in “Gynecological Endocrinology
    L. Falsetti, Deborah Oliveira De Fusco, G. Eleftheriou, B Rosina
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    TLDR Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.
    The drugs finasteride and flutamide are effective in reducing hirsutism in women with polycystic ovary syndrome (PCOS). Both drugs significantly reduced hair growth in all body areas, with flutamide also causing a drop in testosterone and dehydroepiandrosterone sulfate. Finasteride was found to be more effective in reducing hair diameter. The study involved 44 patients who took either drug for 6 months. The study concluded that both drugs are effective treatments for hirsutism in women with PCOS, with flutamide being more effective in reducing hormone levels and inducing dry skin compared to finasteride. However, more research is needed due to the small sample size of the study.
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