Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris
July 2023
in “IntechOpen eBooks”
TLDR The best treatment for Frontal Fibrosing Alopecia and Lichen Planopilaris combines oral and topical medications to reduce symptoms and stop hair loss.
The document discusses the treatment of Frontal Fibrosing Alopecia (FFA) and Lichen Planopilaris (LPP). The goal of treatment is to alleviate symptoms and halt hair loss progression, as hair regrowth is not possible once hair follicle destruction has occurred. Topical corticosteroids and tacrolimus can reduce inflammation but do not clearly slow alopecia. Intralesional corticosteroids may stimulate hair regrowth in some patients, especially for eyebrow alopecia in FFA. Systemic treatments, such as 5-alpha reductase inhibitors, are most effective in stabilizing FFA and promoting hairline regrowth. Hydroxychloroquine and oral immunomodulators are beneficial as oral treatments in LPP. Low-dose oral isotretinoin is the preferred treatment for facial papules in FFA. The combination of oral and topical treatments is the best therapeutic choice.
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