Postmenopausal frontal fibrosing alopecia: A frontal variant of lichen planopilaris
January 1997
in “
Journal of the American Academy of Dermatology
”
![Image of study](/images/research/2a87d766-bfb2-4cd3-b9b8-cc19f843a013/medium/34429.jpg)
TLDR Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.
The study examined the clinical and histopathologic features of frontal fibrosing alopecia (FFA), a condition affecting postmenopausal women characterized by progressive hair loss at the frontal hairline, which is a variant of lichen planopilaris. The study included 16 women with FFA, 13 of whom also experienced significant eyebrow loss. No other sites of lichen planus were found, except in one patient who developed multifocal lichen planopilaris. The condition was slowly progressive, with stabilization observed in five patients. Histologic examination of scalp biopsies from the frontal hairline showed changes identical to those seen in lichen planopilaris, and immunophenotyping showed no significant differences between FFA and the multifocal variant. Treatments, including oral steroids, antimalarials, and hormone replacement therapy, were largely ineffective, though some may temporarily slow progression. The underlying cause of the condition remains unknown.
View this study on jaad.org →
Cited in this study
4 / results![Histopathology of non-scarring alopecia](/images/research/3bc47a88-19ff-4cdc-9a37-41ee2bb51ea9/small/25301.jpg)
research Histopathology of non-scarring alopecia
The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
![Diagnostic and predictive value of horizontal sections of scalp biopsy specimens in male pattern androgenetic alopecia](/images/research/980cbe60-e0eb-4301-83a0-7e87732f2dac/small/2003.jpg)
research Diagnostic and predictive value of horizontal sections of scalp biopsy specimens in male pattern androgenetic alopecia
Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.
![Patterned androgenic alopecia in women](/images/research/48f6fc9e-0b11-4e24-91cb-2d6dbca56bb2/small/12371.jpg)
research Patterned androgenic alopecia in women
"Male-pattern" hair loss is common in women, especially after menopause, and doesn't always mean there's a problem with hormone balance.
![Male Pattern Alopecia A Histopathologic and Histochemical Study](/images/research/ec790ce1-ef8e-4f4f-9c8b-ba6c26b61305/small/25571.jpg)
research Male Pattern Alopecia A Histopathologic and Histochemical Study
Male pattern baldness involves smaller hair follicles, larger oil glands, and other tissue changes, but not major blood supply issues.
Related
6 / resultsresearch Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil
Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.
![Safety and Efficacy of Trimax-360 Serum in Healthy Adult Subjects with Mild to Moderate Alopecia of the Scalp](/images/research/29496019-8a24-4098-ab39-9890562fbf8f/small/13052.jpg)
research Safety and Efficacy of Trimax-360 Serum in Healthy Adult Subjects with Mild to Moderate Alopecia of the Scalp
Trimax-360 Serum, when used for 98 days, safely and effectively improves hair growth, thickness, and density without any side effects.
![Significant Relationship Between Temporal Hair Loss and Other Scalp Areas in Female Pattern Hair Loss](/images/research/8bf491c1-dafc-46ef-9e41-661e865aea44/small/4716.jpg)
research Significant Relationship Between Temporal Hair Loss and Other Scalp Areas in Female Pattern Hair Loss
Temporal hair loss relates to overall scalp hair loss in women.
![The changing patterns of hair density and thickness in South Korean women with hair loss: clinical office-based phototrichogram analysis](/images/research/855dad3e-7773-4efd-807f-66271232fb47/small/16380.jpg)
research The changing patterns of hair density and thickness in South Korean women with hair loss: clinical office-based phototrichogram analysis
South Korean women with hair loss have lower hair density and thickness compared to healthy women.
![HAIR DISEASES](/images/research/1ca13294-13cd-47e7-9dfd-6a45b6e9ae8b/small/22404.jpg)
research HAIR DISEASES
Most hair loss can be diagnosed with patient history and physical exam, and a few common types make up most cases.
![Androgenetic alopecia, trichotrophic substances, and histologic studies of the human scalp](/images/research/2049dc01-0e3b-4d21-895a-c9295be362ad/small/1896.jpg)
research Androgenetic alopecia, trichotrophic substances, and histologic studies of the human scalp
Minoxidil promotes hair growth but exact mechanism is unknown.