Diagnostic and predictive value of horizontal sections of scalp biopsy specimens in male pattern androgenetic alopecia
May 1993
in “Journal of The American Academy of Dermatology”
TLDR Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.
This document summarizes various studies on the diagnostic and predictive value of scalp biopsy specimens in male pattern androgenetic alopecia (MPAA). The studies found that horizontal sections of scalp biopsy specimens are more effective than vertical sections in diagnosing and predicting the progression of MPAA. Follicular structure density and inflammation are correlated with hair regrowth, and patients with higher follicular density have a better chance of hair growth. Topical minoxidil can promote hair growth in patients with MPAA, but it may not work for those with low follicular density. Inflammation is associated with reduced hair regrowth, and anti-inflammatory treatment may be necessary for some patients.
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