Comparison Between Topical Minoxidil 5% Alone Versus Combined With Dutasteride (Topical 0.02% Through Microneedling Or Oral 0.5 Mg) In Treatment Of Androgenetic Alopecia

    October 2024 in “ QJM
    Maram Obeid, Nermeen Samy Abdel Fattah, Mona Mohamed Elfangary, Rania Mahmoud Al Husseni
    From the encyclopedia
    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    Microneedling →

    technique to create small wounds in skin to activate collagen production and hair growth

    Image
    Studysummary In this study, among 30 patients with androgenetic alopecia, topical Minoxidil was effective alone or in combination with either oral or microneedling-applied Dutasteride, with the microneedling approach offering promising results and fewer side effects compared to oral Dutasteride.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    This study compared the efficacy and safety of topical Minoxidil 5% alone versus combined with Dutasteride (either topical 0.02% through microneedling or oral 0.5 mg) in treating androgenetic alopecia (AGA) in 30 patients (24 males, 6 females). Over 16 weeks, all groups showed significant improvement, with the combination treatments (groups B and C) yielding better results in hair density and width than Minoxidil alone (group A). Group C, using topical Dutasteride with microneedling, showed the highest improvement and fewer systemic side effects compared to oral Dutasteride. The study concluded that combining Minoxidil with topical Dutasteride via microneedling is a promising and effective treatment for AGA with minimal side effects.
    Discuss this study in the Community →