Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
April 2021
in “Journal of Medicinal Chemistry”
TLDR Finasteride may affect PNMT, causing side effects.
The study aimed to identify new off-target effects of the hair loss drug finasteride through proteome-wide scale screening. The study found a new potential off-target called PNMT, which could contribute to the drug's side effects. The study emphasizes the importance of understanding drug side effects and the need for further research to improve drug safety.
View this study on pubs.acs.org →
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