The prevalence of metabolic disorders in various phenotypes of polycystic ovary syndrome: a community based study in Southwest of Iran
September 2014
in “Reproductive Biology and Endocrinology”
TLDR Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.
In a 2014 study involving 646 reproductive-aged women in Southwest Iran, Ramezani Tehrani et al. found that different phenotypes of polycystic ovary syndrome (PCOS) exhibited varying levels of metabolic disturbances. Women with phenotype A (oligo/anovulation + hyperandrogenism + polycystic ovaries) and phenotype C (hyperandrogenism + polycystic ovaries) had higher insulin levels and insulin resistance. Phenotype A also had higher levels of cholesterol, low-density lipoprotein, triglycerides, and glucose, while metabolic syndrome was more prevalent in phenotype B (oligo/anovulation + hyperandrogenism). The study concluded that the severest phenotype of PCOS, which includes all three components, showed the highest level of metabolic disturbances, indicating a need for metabolic screening in these patients.
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