The effects of pro-, pre-, and synbiotics supplementation on polycystic ovary syndrome: an umbrella review of meta-analyses of randomized controlled trials

    September 2023 in “ Frontiers in Nutrition ”
    Sepide Talebi, Sheida Zeraattalab-Motlagh, Yahya Jalilpiran‬, Nastaran Payandeh, Shakila Ansari, Hamed Mohammadi, Kurosh Djafarian, Mahsa Ranjbar, Sara Sadeghi, Mahdiyeh Taghizadeh, Sakineh Shab‐Bidar
    TLDR Pro-, pre-, and synbiotics may help with PCOS, but more research is needed.
    The umbrella review of meta-analyses of randomized controlled trials on the effects of pro-, pre-, and synbiotics supplementation on polycystic ovary syndrome (PCOS) found that while there were beneficial effects on some PCOS-related outcomes, the certainty of the evidence was rated as low to very low. This indicates that the current findings are not robust, and further well-designed randomized controlled trials are needed to confirm these results in women with PCOS.
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