The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial
August 2003
in “British Journal of Dermatology”
TLDR Minoxidil and pyrithione zinc combo most effectively increases hair density.
A 6-month randomized controlled trial was conducted on 200 healthy men with Hamilton-Norwood type III vertex or type IV baldness to assess the hair growth benefits of a 1% pyrithione zinc shampoo compared to a 5% minoxidil topical solution, a placebo shampoo, and a combination of the two. Hair count results showed a significant increase in total visible hair counts for the 1% pyrithione zinc shampoo, the 5% minoxidil topical solution, and the combination treatment groups relative to the placebo shampoo after 9 weeks of treatment. The study concluded that daily use of a 1% pyrithione zinc shampoo over a 26-week treatment period can result in a modest and sustained improvement in hair growth. The combination of minoxidil and pyrithione zinc was found to be more effective in increasing hair density than either treatment alone.
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