Retrospective Analysis of Systemic Corticosteroids for Alopecia Areata in Pediatric Patients

    December 2020 in “ Dermatology Archives
    Shant Tamazian, Rogers Rachel, Castelo-Soccio Leslie
    TLDR Systemic steroids temporarily improve severe alopecia areata in children but often lead to relapse.
    This retrospective study analyzed the efficacy and safety of systemic corticosteroid therapy in 82 pediatric patients with alopecia areata (AA) at the Children's Hospital of Philadelphia. Patients with severe AA (SALT scores ≥ 50) showed significant improvement in hair regrowth after treatment, but most relapsed within 4-5 months. No serious adverse effects were reported, although there was a statistically significant increase in weight percentiles. The study highlighted the temporary effectiveness of systemic steroids in severe cases of AA in children, despite the high relapse rate.
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