Sublingual minoxidil for the treatment of male and female pattern hair loss: a randomized, double‐blind, placebo‐controlled, phase 1B clinical trial
January 2022
in “Journal of The European Academy of Dermatology and Venereology”
TLDR Sublingual minoxidil safely promotes hair growth.
The document reports on a randomized, double-blind, placebo-controlled, phase 1B clinical trial of sublingual minoxidil for the treatment of male and female pattern hair loss. The study found that sublingual minoxidil was safe and effective in promoting hair growth, with a significant increase in hair count observed in the treatment group compared to the placebo group. The authors suggest that sublingual minoxidil may be a promising treatment option for individuals with hair loss. Further studies are needed to determine the optimal dose of sublingual minoxidil and compare its efficacy to oral minoxidil.
View this study on minerva-access.unimelb.edu.au →
Cited in this study
research Treatment of male and female pattern hair loss with sublingual minoxidil: a retrospective case‐series of 64 patients
Sublingual minoxidil effectively treats hair loss with mild side effects.
research Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil treatment in Brazilian female pattern hair loss patients
Hair enzyme activity predicts minoxidil success in Brazilian women with hair loss.
research Effectiveness and safety of low-dose oral minoxidil in male androgenetic alopecia
Low-dose oral minoxidil effectively improves male hair loss with mild side effects.
research Sulfation of minoxidil by multiple human cytosolic sulfotransferases
Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
research Hemodynamic effects of minoxidil following intravenous infusions in untreated hypertensive patients.
Minoxidil given intravenously caused small changes in diastolic blood pressure and increased heart rate at higher concentrations in patients with high blood pressure.
research The Pharmacokinetics of 2.5- to 10-mg Oral Doses of Minoxidil in Healthy Volunteers
This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.
research Pharmacology and Pharmacokinetics of Minoxidil
Minoxidil treats high blood pressure and side effects can be managed.