A One-Year Exploratory Randomized, Controlled, Multicentric Pilot Study Evaluating the Efficacy and Tolerance of an Anti-Hair Loss Serum Containing Silybum Marianum Extract, Manganese PCA, and Lespedeza Capitata Extract Following Hair Transplantation in Men with Androgenic Alopecia

    June 2026 in “ Frontiers in Medicine ”
    Daniel Ortega Quijano, Alba Gómez Zubiaur, Marine Babin … V. Mengeaud
    Studysummary In this randomized controlled trial, daily use of a hair serum containing plant extracts and manganese PCA improved scalp tightness, reduced discomfort, and enhanced hair growth quality in men post-hair transplant, suggesting its efficacy as a dermocosmetic adjuvant for long-term hair care.
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    Research cited in this study 10

    1. A Well-Tolerated Hair Serum Containing New Natural Active Ingredients Reduced Hair Loss and Improved Quality of Life in Women With Chronic Telogen Effluvium: A 16-Week Controlled Study Journal of Cosmetic Dermatology · 2024
    2. New Plant Extracts Exert Complementary Anti-Hair Loss Properties in Human In Vitro and Ex Vivo Models Journal of Cosmetic Dermatology · 2024
    3. Hair Transplantation: Basic Overview Journal of The American Academy of Dermatology · 2021
    4. Old Friend or New Ally: A Comparison of Follicular Unit Transplantation and Follicular Unit Excision Methods in Hair Transplantation Dermatologic Surgery · 2020
    5. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    6. Highly Efficient and Compatible Shampoo for Use After Hair Transplant Clinical, cosmetic and investigational dermatology · 2015
    7. Hair Transplantation Update Seminars in Cutaneous Medicine and Surgery · 2015
    8. Hair Restoration Surgery: The State of the Art Aesthetic Surgery Journal · 2012
    9. Hair Transplantation Update Dermatologic Clinics · 2012
    10. Dermocosmetic Aspects of Hair and Scalp ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005