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research A one-year exploratory randomized, controlled, multicentric pilot study evaluating the efficacy and tolerance of an anti-hair loss serum containing Silybum marianum extract, manganese PCA, and Lespedeza capitata extract following hair transplantation in men with androgenic alopecia

June 2026 in “Frontiers in Medicine”

In this randomized controlled trial, daily use of a hair serum containing plant extracts and manganese PCA improved scalp tightness, reduced discomfort, and enhanced hair growth quality in men post-hair transplant, suggesting its efficacy as a dermocosmetic adjuvant for long-term hair care.

A One-Year Exploratory Randomized, Controlled, Multicentric Pilot Study Evaluating the Efficacy and Tolerance of an Anti-Hair Loss Serum Containing Silybum Marianum Extract, Manganese PCA, and Lespedeza Capitata Extract Following Hair Transplantation in Men with Androgenic Alopecia

research Supplementary file 1_A one-year exploratory randomized, controlled, multicentric pilot study evaluating the efficacy and tolerance of an anti-hair loss serum containing Silybum marianum extract, manganese PCA, and Lespedeza capitata extract following hair transplantation in men with androgenic alopecia.docx

June 2026 in “Figshare”

This study found that using a hair serum with specific plant-derived extracts and manganese PCA improved scalp condition and hair growth in men after hair transplantation compared to controls.

research Interest of an anti-hair loss serum containing Silybum marianum extract, manganese pyrrolidone carboxylic acid (PCA), and a Lespedeza capitata extract in the management of post-cancer treatment alopecia: an international real-world study

January 2026 in “EJC Skin Cancer”

This research underscores the significant challenge of managing hair loss after cancer treatment and explores the need to evaluate new topical strategies to promote faster and higher-quality hair regrowth, as existing recovery processes are often slow and sometimes incomplete.

Interest of Silybum Marianum Extract, Manganese PCA, and Lespedeza Capitata Extract in a New Anti-Hair Loss Serum to Stimulate Hair Growth and Prolong Anagen Phase

research 586 Interest of Silybum marianum extract, Manganese PCA and Lespedeza capitata extract in a new anti-hair loss serum to stimulate hair growth and prolong anagen phase

November 2022 in “Journal of Investigative Dermatology”

In this study, a serum containing Silybum marianum extract, Manganese PCA, and Lespedeza capitata extract improved hair growth and prolonged the anagen phase in a human scalp skin model.

research ESDR586 - Interest of Silybum marianum extract, Manganese PCA and Lespedeza capitata extract in a new anti-hair loss serum to stimulate hair growth and prolong anagen phase

September 2022

The serum with these ingredients may help reduce hair loss and promote growth.

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community Best science-backed supplements for androgenetic alopecia? Looking for real evidence

7 months ago

The conversation discusses treatments for androgenetic alopecia, focusing on evidence-based supplements to complement finasteride. Suggestions include oral minoxidil, saw palmetto, pumpkin seed oil, tocotrienols, and various other supplements, while emphasizing the importance of scientific backing and cautioning against saw palmetto if already using finasteride.

community So what other supplements should you take alongside finasteride.

4 upvotes 1 year ago

The conversation discusses using finasteride for hair loss and considers additional supplements like vitamin D3, melatonin, zinc, biotin, and minoxidil. There is debate over zinc's effectiveness, with some suggesting it may not be beneficial for hair loss.

community Bruteforcing alopecia or the new advent of science progress

22 upvotes 1 year ago

Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.

community Melatonin emerging as new treatment for androgenic alopecia?

in Update 35 upvotes 1 year ago

Melatonin is being considered as a potential treatment for androgenic alopecia, with some users discussing its effects and combining it with other treatments like minoxidil and finasteride. Concerns about melatonin's impact on hormones and side effects from other treatments like ketoconazole were also discussed.

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