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research A one-year exploratory randomized, controlled, multicentric pilot study evaluating the efficacy and tolerance of an anti-hair loss serum containing Silybum marianum extract, manganese PCA, and Lespedeza capitata extract following hair transplantation in men with androgenic alopecia

June 2026 in “Frontiers in Medicine”

In this randomized controlled trial, daily use of a hair serum containing plant extracts and manganese PCA improved scalp tightness, reduced discomfort, and enhanced hair growth quality in men post-hair transplant, suggesting its efficacy as a dermocosmetic adjuvant for long-term hair care.

research Early results in the use of injectable ACell suspended in arterial blood serum/PRP in retarding hair loss/re-growth of miniaturizing scalp hairs

1 citations , May 2011 in “Hair transplant forum international”

This article discusses the potential of platelet rich plasma injections for treating hair loss but reports no new clinical results, emphasizing the need for further research.

research Association Between Serum Zinc, Vitamin D, and Ferritin Levels and Hair Loss: A Cross-Sectional Study of Patients at Al-Ajilat Central Clinic

November 2025 in “Khalij-Libya Journal of Dental and Medical Research”

In this study, Libyan patients with diffuse hair loss were found to have significantly lower levels of zinc, ferritin, and vitamin D compared to those without hair loss, suggesting a possible link between these micronutrient deficiencies and hair loss.

research Efficacy of Dr. SKS hair booster serum for the treatment of hair loss in COVID-19 induced persistent telogen effluvium

March 2024 in “International journal of research in medical sciences”

In this study, researchers reported that intradermal injections of Dr. SKS hair booster serum improved hair growth and patient satisfaction in individuals experiencing COVID-19-induced persistent telogen effluvium, with increased benefits observed over six months.

research Hair loss and serum zinc values among Arab females in Al Ain region, United Arab Emirates.

6 citations , January 2008 in “PubMed”

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Community Join

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community 22M: Hair Loss Worsening Despite Using Prescribed Serum and Shampoo

in Basic Questions 61 upvotes 4 months ago

A 22-year-old is experiencing worsening hair loss despite using a doctor-prescribed serum and shampoo. They are seeking advice on additional treatments like Minoxidil, finasteride, or RU58841.

community If you could get for Christmas your own personalised topical anti hair loss serum that has the best the current science can offer, what would it contain and at what concentration?

2 upvotes 1 year ago

A personalized topical anti-hair loss serum could include high-dose setipiprant, high-dose CB 03-01, low-dose finasteride, minoxidil, latanoprost, and tretinoin. These ingredients are suggested for their potential effectiveness in promoting hair growth.

community Is there a reason why hair serums (The Ordinary, Vichy, etc.) are never part of a serious hair loss stack?

40 upvotes 4 months ago

Hair serums like The Ordinary and Vichy are seen as minor additions to hair loss treatments but are not considered effective on their own compared to well-studied options like Minoxidil and Finasteride. They may improve scalp health or hair strand quality but are not reliable for significant hair regrowth or combating male pattern baldness.

community Has anyone tried nicotinamide serum for inflammatory hair loss.

3 upvotes 1 year ago

Nicotinamide serum is discussed for its potential benefits in reducing inflammation related to hair loss. One user combines it with minoxidil for hair growth.

community Serum DHT CAN'T cause hair loss. Sebum DHT is a better measurement.

in Research/Science 19 upvotes 2 years ago

Serum DHT is mostly inactive; sebum DHT is a better measure for hair loss. Users discuss using finasteride, dutasteride, and topical treatments like KX826 and RU58841 for better scalp DHT suppression.

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Learn

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learn zinc PCA

Can a zinc deficiency directly cause hair thinning or increased shedding? Studies link low serum zinc to diffuse shedding and alopecia areata, and severe deficiency states cause hair loss that reverses when zinc is replaced. The evidence is mostly observational, the one supplementation study was small and uncontrolled, and zinc is not a treatment for pattern hair loss.

learn Selenium

Is Selenium more effective when taken orally or applied topically in shampoos or serums? The two are not interchangeable and the evidence points the other way from the common assumption: topical selenium disulfide shampoo has clinical trial support for dandruff and seborrheic dermatitis, while oral selenium supplements have no reliable evidence for hair growth in people who are not deficient, and excess intake is a recognised cause of hair loss.

learn Capixyl

What products can I find Capixyl in and what is the best way to use it? Capixyl is a cosmetic ingredient found in lotions, serums and shampoos. Its evidence comes mainly from its manufacturer, and brands' hair-loss claims have not been independently tested.

learn Finasteride

Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

learn Dutasteride

5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

learn Vitamin D

Vitamin made in the skin from sunlight, also taken as a supplement

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Vitamin B12

How can you tell if your hair loss is related to low Vitamin B12 levels? Hair loss may indicate low Vitamin B12 if accompanied by fatigue and anemia symptoms.

learn Hair Transplant

What is shock loss after a hair transplant? Shock loss is shedding of existing hair near the transplant area after surgery; it is usually temporary and regrows over a few months.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

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