Skin Manifestations of Hypothyroidism: A Clinical Study

In the clinical study conducted on 100 patients with hypothyroidism, 63% exhibited skin manifestations. The most common skin changes observed were xerosis (acquired ichthyosis) and diffuse hair loss (telogen effluvium), affecting 38.09% and 34.8% of patients, respectively. Other frequent skin conditions included melasma (14.28%), chronic urticaria (14.28%), and generalized pruritus (11.1%). Less common associated disorders were alopecia areata (6.34%), vitiligo (4.76%), lichen planus (3.17%), and xanthelasma palpebrarum (1.58%). The study concluded that recognizing these skin manifestations can aid in the early detection of an underlying hypothyroid condition.