Signal Mining for Non-Bleeding Adverse Events in Novel Oral Anticoagulants: A Pharmacovigilance Study Based on the FAERS Database

    July 2025
    Guimu Guo, Ying Song, Yunda Chen, Jinhua Zhang
    Studysummary This study found that non-bleeding adverse events associated with NOACs affect multiple organ systems, emphasizing the importance of clinical vigilance. Specific NOACs like dabigatran, apixaban, edoxaban, and rivaroxaban were linked to distinct adverse reactions, including metabolic imbalances, thyroid disorders, and menstrual irregularities.
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    Research cited in this study 1

    1. Traditional Anticoagulants and Hair Loss: A Role for Direct Oral Anticoagulants? A Review of the Literature Drugs - Real World Outcomes · 2016