Serum Androgens and Genetic Linkage Analysis in Early Onset Androgenetic Alopecia

The document titled "Serum Androgens and Genetic Linkage Analysis in Early Onset Androgenetic Alopecia" discusses the causes of androgenetic alopecia (AGA) and proposes various genetic models to explain its development. The study found a significant association between early onset AGA and the androgen receptor gene through genetic linkage analysis on 45 families. The study also suggests that males deficient in type II 5 alpha reductase enzyme do not develop AGA, indicating the role of genetic factors and androgen metabolism in the development of AGA. The study investigated the relationship between serum androgen levels and early onset AGA and found a potential genetic component to the condition. The study suggests that targeting androgen levels may be a potential treatment for AGA.