Case Report: Secondary Syphilitic Alopecia Following Non-Penetrative Sexual Contact: A Case of Initial Misdiagnosis

    April 2026 in “ Frontiers in Medicine ”
    Yuyu Deng, C J Li, Lifang Cheng … Xiaohua Tao
    Studysummary This case study reports a 26-year-old male with secondary syphilitic alopecia misdiagnosed as alopecia areata, likely contracted through non-penetrative sexual contact. Effective treatment with intramuscular benzathine penicillin G led to complete hair regrowth within three months.
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    Research cited in this study 4

    1. Epidemiological, Clinical, and Trichoscopic Features of Syphilitic Alopecia: A Retrospective Analysis and Systematic Review Frontiers in Medicine · 2022
    2. Syphilitic Alopecia: Uncommon Trichoscopic Findings Dermatology practical & conceptual · 2017
    3. Syphilitic Alopecia: Case Reports and Trichoscopic Findings Skin appendage disorders · 2017
    4. Syphilitic Alopecia: A Report of 5 Cases and a Review of the Literature Actas Dermo-Sifiliográficas · 2013